兽药科学系

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  • 袁宗辉
  • 系所

    兽药学系
  • 职称

    二级教授
  • 办公房间

    国家兽药残留基准实验室114室
  • 电子邮件

    yuan5802@mail.hzau.edu.cn
  • 讲授课程

    《兽医药理学A》等

个人简介

袁宗辉, 男,1958年2月23日生,湖北省天门市人。1981年12月毕业于华中农学院兽医专业(本科)。1987年12月在华南农业大学获农学博士学位,成为中国大陆第一个兽医药理学及毒理学博士。现任华中农业大学二级岗教授、博士生导师,兽药学系主任,西班牙皇家兽医科学院外籍院士、国务院食品安全委员会专家委员会、食品安全国家标准审评委员会、国家农产品质量安全风险评估专家委员会、中国兽药典委员会、全国兽药残留和耐药性专家委员会、农业部兽药审评委员会等委员。
先后承担国家973、支撑(攻关)、重点研发、国际科技合作、国家自然科学基金、部省级重点科研和企业合作开发等项目,取得一批有影响的成果。将放射示踪与高分辨质谱技术相结合,攻克未知代谢物/残留物鉴定和定量测定等关键技术,揭示喹噁啉类、苄胺嘧啶类等在畜禽鱼体内物料平衡、体内过程及其种属特点,阐明代谢谱、代谢路径和残留规律,确定残留标志物,为食品安全评价和风险管控奠定科学基础。研制兽药残留检测核心试剂和标准品,解决萃取、基质干扰等分析难题,先后建立18类208种残留物的定量/确证检测法,研制能同时检测7类61种抗生素残留的微孔板和23类164种残留物的ELISA试剂盒及试纸条,在全国兽药残留监控计划中应用。动物源食品中主要兽药残留物高效检测关键技术获国家技术发明二等奖,喹噁啉类食品安全性评价与风险管控技术研发、兽药残留检测方法标准研究制订等获湖北省、教育部科技进步奖一等奖。主持制订兽药残留检测方法国家标准48项、备案产品17个。获授权发明专利75件、另申报38件,申请保藏物种46个。发表学术论文360余篇。以第一或责任作者发表SCI论文200余篇。主编专著3部,参编13部。1997年被评为农业部中青年有突出贡献专家,2008年享受国务院政府特殊津贴,2012年当选全国优秀科技工作者(终身荣誉)、入选湖北省高端人才引领培养计划第一层次,2013年当选湖北省创新创业人才。
1997和2001年,分别在美国肯塔基大学和罗德岛大学做访问教授。在兽药残留与食品安全、抗菌药耐药性等领域,与美国、法国、比利时、西班牙、以色列等国科学家保持长期合作关系。先后14次以中国代表团成员身份参加国际食品法典大会和兽药残留法典会议。2012年入选联合国粮农组织和世界卫生组织食品添加剂联合专家委员会专家,主持制订拉沙洛西等最高残留限量。2014年当选西班牙皇家兽医科学院外籍院士。
创建并领导国家兽药残留基准实验室(华中农业大学),华中农业大学国家兽药安全评价实验室,农业部兽药残留检测重点实验室,农业部畜禽产品质量安全风险评估实验室(武汉)。培养一批中青年学术带头人和专业骨干。建立和承担基础兽医学博、硕士生多门专业课,已培养博士40名,硕士142名,出站博士后3名。指导的学位论文,一篇获全国百篇优秀博士论文提名奖,11篇获湖北省优秀博/硕士生学位论文指导奖。主持《兽医药理学》(本科生必修课)被评为湖北省精品课程。指导访问学者和进修生4人。
现任中国畜牧兽医学会常务理事、兽医药理学及毒理学分会理事长,中国毒理学会兽医毒理学专业委员会副理事长,兽用化学药品产业技术创新联盟(科技部批准的唯一兽药试点联盟)副理事长兼秘书长,Front Vet Pharmacol Toxicol副主编,J Vet Pharmacol Therap、中国农业科学等8个杂志编委,J Food Agri Chem、Chrom A、Anal Bioanal Chem、畜牧兽医学报等17个杂志特约审稿人。应邀撰写文献综述9篇,做大会或特邀报告93次,科普报告99次。

教育经历

1975.06. 原籍高中毕业。
1978.03-1981.12. 华中农业大学兽医专业本科生。
1982.01-1984.12. 华中农业大学兽医药理学及毒理学硕士生。导师:张祖荫教授。
1985.01.-1987.12. 华南农业大学兽医药理学及毒理学博士生。导师:冯淇辉教授。我国第一个兽医药理学及毒理学博士。

工作经历

1975.06.-1978.02. 原籍国营农场务农、做工和教书。
1988.01.-1993.05. 华南农业大学兽医药理研究室讲师、副教授和硕士生导师。
1993.06.-1994.05. 深圳华宝集团股份公司华大兽药有限公司厂长。
1994.06.-至今 华中农业大学畜牧兽医学院教授,博士生导师,国家兽药残留基准实验室(HZAU)、国家兽药安全评价实验室、农业部兽药残留检测重点实验室主任、农业部农产品质量安全风险评估实验室(武汉)主任,华中农业大学兽药研究所所长,兽药科学系主任。

研究领域

药物代谢动力学,兽药残留与食品安全,抗菌耐药性,新兽药研发等。

科研成果

A著作类
1. 袁宗辉主编。家禽无公害用药技术(22.5万字)。北京:中国农业出版社,第1版,2003
2. 袁宗辉主编。饲料药物学(120万字)。北京:中国农业出版社,第1版,2001 (国家科学技术学术著作出版基金项目)
3. 袁宗辉主编。动物用药指南(35万字)。北京:中国农业出版社,第1版,1998
B论文类
1.  Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring organoarsenic compounds in edible chicken and pork and feed Food Chemistry, v 197, p 821-828, April 15, 2015 2016.01
2.  Integrated Transcriptional and Proteomic Analysis of Growth Hormone Suppression Mediated by Trichothecene T-2 Toxin in Rat GH3 Cells TOXICOLOGICAL SCIENCES 2015.12
3.  Metabolism, Distribution, and Elimination of Mequindox in Pigs, Chickens, and Rats JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015.12
4 . Two-generation reproduction and teratology studies of feeding aditoprim in Wistar rats JOURNAL OF APPLIED TOXICOLOGY 2015.11
5.  Mechanism of adrenocortical toxicity induced by quinocetone and its bidesoxy-quinocetone metabolite in porcine adrenocortical cells in vitro FOOD AND CHEMICAL TOXICOLOGY 2015.11
6.  Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies JOURNAL OF APPLIED TOXICOLOGY 2015.10
7 . Microbiological toxicity of tilmicosin on human colonic microflora in chemostats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2015.09
8.  A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for 3-methyl-quinoxaline-2-carboxylic acid in edible animal tissues ANALYTICAL METHODS 2015.09
9.  Discovery of the new marker residue of olaquindox in swine, broiler and carp JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2015.07
10.  Integration of PK/PD for dose optimization of Cefquinome against Staphylococcus aureus causing septicemia in cattle FRONTIERS IN MICROBIOLOGY 2015.07
11. Metabolic Disposition and Elimination of Cyadox in Pigs, Chickens, Carp, and Rats JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2015.07
12. Deoxidation Rates Play a Critical Role in DNA Damage Mediated by Important Synthetic Drugs, Quinoxaline 1,4-Dioxides (vol 28, pg 470, 2015) CHEMICAL RESEARCH IN TOXICOLOGY 2015.06
13. Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2015.05
14. Development and validation of a multi-residue screening method for veterinary drugs, their metabolites and pesticides in meat using liquid chromatography-tandem mass spectrometry FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2015.05
15. Deoxidation Rates Play a Critical Role in DNA Damage Mediated by Important Synthetic Drugs, Quinoxaline 1,4-Dioxides CHEMICAL RESEARCH IN TOXICOLOGY 2015.04
16. Metabolism, Distribution, and Elimination of Mequindox in Pigs, Chickens, and Rats Journal of Agricultural and Food Chemistry, v 63, n 44, p 9839-9849, November 11, 2015 2015.01
17. Metabolic Disposition and Elimination of Cyadox in Pigs, Chickens, Carp, and Rats Journal of Agricultural and Food Chemistry, v 63, n 22, p 5557-5569, June 10, 2015 2015.01
18. Development and validation of a multi-residue screening method for veterinary drugs, their metabolites and pesticides in meat using liquid chromatography-tandem mass spectrometry Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, v 32, n 5, p 686-701, May 4, 2015 2015.01
19. Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, v 988, p 143-148, April 05, 2015 2015.01
20. Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2014.12
21. Crosstalk of JNK1-STAT3 is critical for RAW264.7 cell survival CELLULAR SIGNALLING 2014.12
22. Tissue Depletion of Quinocetone and Its Five Major Metabolites in Pigs, Broilers, and Carp Fed Quinocetone Premix JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014.11
23. Structure-Function Analysis of Porcine Cytochrome P450 3A29 in the Hydroxylation of T-2 Toxin as Revealed by Docking and Mutagenesis Studies PLOS ONE 2014.10
24. Evaluation of matrix solid-phase dispersion extraction for 11 beta-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry JOURNAL OF SEPARATION SCIENCE 2014.10
25. Biodegradable nanoparticles for intracellular delivery of antimicrobial agents JOURNAL OF CONTROLLED RELEASE 2014.07
26. Benefits and risks of antimicrobial use in food-producing animals FRONTIERS IN MICROBIOLOGY 2014.07
27. Metabolic disposition and excretion of quinocetone in rats, pigs, broilers, and carp FOOD AND CHEMICAL TOXICOLOGY 2014.07
28. Antibiotic alternatives: the substitution of antibiotics in animal husbandry? FRONTIERS IN MICROBIOLOGY?? 2014.06
29. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues FOOD CHEMISTRY 2014.04
30. Evaluation of matrix solid-phase dispersion (MSPD) extraction for multi-fenicols determination in shrimp and fish by liquid chromatography-electrospray ionisation tandem mass spectrometry FOOD CHEMISTRY 2014.01
31. Metabolism, Distribution, and Excretion of Deoxynivalenol with Combined Techniques of Radiotracing, High-Performance Liquid Chromatography Ion Trap Time-of-Flight Mass Spectrometry, and Online Radiometric Detection JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2014.01
32. High Risk of Embryo-Fetal Toxicity: Placental Transfer of T-2 Toxin and Its Major Metabolite HT-2 Toxin in BeWo Cells TOXICOLOGICAL SCIENCES 2014.01
33. A physiologically based pharmacokinetic model for the prediction of the depletion of methyl-3-quinoxaline-2-carboxylic acid, the marker residue of olaquindox, in the edible tissues of pigs JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2014.01
34. Evaluation of matrix solid-phase dispersion extraction for 11 β-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry Journal of Separation Science, v 37, n 18, p 2574-2582, 2014 2014.01
35. Metabolism, distribution, and excretion of deoxynivalenol with combined techniques of radiotracing, high-performance liquid chromatography ion trap time-of-flight mass spectrometry, and online radiometric detection Journal of Agricultural and Food Chemistry 2014.01
36. A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for sulfonamides in edible animal tissues Food Chemistry 2014.01
37. Biodegradable nanoparticles for intracellular delivery of antimicrobial agents Journal of Controlled Release 2014.01
38. Development of a novel genetically modified bioluminescent-bacteria-based assay for detection of fluoroquinolones in animal-derived foods Analytical and Bioanalytical Chemistry 2014.01
39. Evaluation of matrix solid-phase dispersion extraction for 11 β-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry Journal of Separation Science 2014.01
40. Tissue depletion of quinocetone and its five major metabolites in pigs, broilers, and carp fed quinocetone premix Journal of Agricultural and Food Chemistry 2014.01
41. Mechanism of Porcine Liver Xanthine Oxidoreductase Mediated N-Oxide Reduction of Cyadox as Revealed by Docking and Mutagenesis Studies PLOS ONE 2013.12
42. Impact of cyadox on human colonic microflora in chemostatmodelsle REGULATORY TOXICOLOGY AND PHARMACOLOGY 2013.12
43. Development of a direct ELISA based on carboxy-terminal of penicillin-binding protein BlaR for the detection of beta-lactam antibiotics in foods ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2013.11
44. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction method for the simultaneous determination of sudan dyes and their metabolites in the edible tissues and eggs of food-producing animals JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2013.11
45. Antibacterial action of quinolones: From target to network EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2013.09
46. Trichothecenes: Structure-Toxic Activity Relationships CURRENT DRUG METABOLISM 2013.07
47. Genotoxicity evaluation of Mequindox in different short-term tests FOOD AND CHEMICAL TOXICOLOGY 2013.03
48. Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo FOOD AND CHEMICAL TOXICOLOGY 2013.01
49. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction and auto solid-phase clean-up method for the determination of Fusarium toxins in animal derived foods JOURNAL OF CHROMATOGRAPHY A 2013.01
50. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction method for the simultaneous determination of sudan dyes and their metabolites in the edible tissues and eggs of food-producing animals Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2013.01
51. Development of a liquid chromatography-tandem mass spectrometry with ultrasound-assisted extraction and auto solid-phase clean-up method for the determination of Fusarium toxins in animal derived foods Journal of Chromatography A 2013.01
52. Development of a direct ELISA based on carboxy-terminal of penicillin-binding protein BlaR for the detection of β-lactam antibiotics in foods Analytical and Bioanalytical Chemistry 2013.01
53. Evaluation of matrix solid-phase dispersion (MSPD) extraction for multi-fenicols determination in shrimp and fish by liquid chromatography- electrospray ionisation tandem mass spectrometry Food Chemistry 2013.01
54. Development of a sensitive and robust liquid chromatography coupled with tandem mass spectrometry and a pressurized liquid extraction for the determination of aflatoxins and ochratoxin A in animal derived foods :JournalofChromatographyA 2012.01
55. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for the screening of tylosin and tilmicosin in muscle, liver, milk, honey and eggs Journal of Agricultural and Food Chemistry 2012.01
56. Development of an accelerated solvent extraction, ultrasonic derivatisation LC-MS/MS method for the determination of the marker residues of nitrofurans in freshwater fish Food Additives and Contaminants - Part A Chemistry, Analysis,Control, Exposure and Risk Assessment 2012.01
57. Determination of 17 macrolide antibiotics and avermectins residues in meat with accelerated solvent extraction by liquid chromatography-tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2012.01
58. Simultaneous determination of 15 aminoglycoside(s) residues in animal derived foods by automated solid-phase extraction and liquid chromatography-tandem mass spectrometry Food Chemistry 2012.01
59. Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2012.01
60. Development of a sensitive and robust liquid chromatography coupled with tandem mass spectrometry and a pressurized liquid extraction for the determination of aflatoxins and ochratoxin A in animal derived foods JOURNAL OF CHROMATOGRAPHY A 2012.01
61. In Vitro Development and Transfer of Resistance to Chlortetracycline in Bacillus subtilis JOURNAL OF MICROBIOLOGY 2012.01
62. Development of Quinoxaline 1, 4-Dioxides Resistance in Escherichia coli and Molecular Change under Resistance Selection PLOS ONE 2012.01
63. Key genetic elements and regulation systems in methicillin-resistant Staphylococcus aureus FUTURE MICROBIOLOGY 2012.01
64. Inhibitors targeting on cell wall biosynthesis pathway of MRSA MOLECULAR BIOSYSTEMS 2012.01
65. Development and Validation of an Indirect Competitive Enzyme-Linked Immunosorbent Assay for the Screening of Tylosin and Tilmicosin in Muscle, Liver, Milk, Honey and Eggs JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2012.01
66. Simultaneous determination of 15 aminoglycoside(s) residues in animal derived foods by automated solid-phase extraction and liquid chromatography-tandem mass spectrometry FOOD CHEMISTRY 2012.01
67. Determination of 17 macrolide antibiotics and avermectins residues in meat with accelerated solvent extraction by liquid chromatography-tandem mass spectrometry JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2012.01
68. Development of an accelerated solvent extraction, ultrasonic derivatisation LC-MS/MS method for the determination of the marker residues of nitrofurans in freshwater fish FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2012.01
69. JAK/STAT Pathway Plays a Critical Role in the Proinflammatory Gene Expression and Apoptosis of RAW264.7 Cells Induced by Trichothecenes as DON and T-2 Toxin TOXICOLOGICAL SCIENCES 2012.01
70. Two generation reproduction and teratogenicity studies of feeding quinocetone fed to Wistar rats FOOD AND CHEMICAL TOXICOLOGY 2012.01
71. Pharmacokinetics of tulathromycin and its metabolite in swine administered with an intravenous bolus injection and a single gavage JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2012.01
72. mRNA expression profiles of P450 3A enzymes in the liver and small intestine of the domestic pig RESEARCH IN VETERINARY SCIENCE?? 2012.01
73. Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2012.01
74. The Role of RamA on the Development of Ciprofloxacin Resistance in Salmonella enterica Serovar Typhimurium PLOS ONE 2011.01
75. Metabolic Pathways of Ochratoxin A CURRENT DRUG METABOLISM 2011.01
76. The metabolism of olaquindox in rats, chickens and pigs TOXICOLOGY LETTERS 2011.01
77. Long-term mequindox treatment induced endocrine and reproductive toxicity via oxidative stress in male Wistar rats TOXICOLOGY AND APPLIED PHARMACOLOGY 2011.01
78. In vitro biotransformation and investigation of metabolic enzymes possibly responsible for the metabolism of bisdesoxyolaquindox in the liver fractions of rats, chicken, and pigs TOXICOLOGY 2011.01
79. Metabolites and JAK/STAT pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox TOXICOLOGY 2011.01
80. The physiologic and phenotypic alterations due to macrolide exposure in Campylobacter jejuni INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY 2011.01
81. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction method for the determination of benzimidazole residues in edible tissues JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
82. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
83. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction for determination of glucocorticoid residues in edible tissues JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
84. Development of a high-performance liquid chromatography method for the simultaneous quantification of four organoarsenic compounds in the feeds of swine and chicken JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
85. Determination of sodium nifurstyrenate and nitrovin residues in edible food by liquid chromatography-tandem mass spectrometry after ultrasound-assisted extraction JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2011.01
86. Identification of carbadox metabolites formed by liver microsomes from rats, pigs and chickens using high-performance liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2011.01
87. Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2011.01
88. A comparison of hepatic in vitro metabolism of T-2 toxin in rats, pigs, chickens, and carp XENOBIOTICA 2011.01
89. Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar rats FOOD AND CHEMICAL TOXICOLOGY 2011.01
90. Simultaneous determination of malachite green, gentian violet and their leuco-metabolites in shrimp and salmon by liquid chromatography-tandem mass spectrometry with accelerated solvent extraction and auto solid-phase clean-up FOOD CONTROL 2011.01
91. Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni MICROBIAL PATHOGENESIS 2011.01
92. Simultaneous determination of lincomycin and spectinomycin residues in animal tissues by gas chromatography-nitrogen phosphorus detection and gas chromatography-mass spectrometry with accelerated solvent extraction FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2011.01
93. Development and validation on indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2011.01
94. Comparison of the substrate kinetics of pig CYP3A29 with pig liver microsomes and human CYP3A4 BIOSCIENCE REPORTS 2011.01
95. Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2011.01
96. A chronic toxicity study of cyadox in Wistar rats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2011.01
97. Inhibition of cytochrome P450 2A participating in coumarin 7-hydroxylation in pig liver microsomes JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2011.01
98. Analytical determination and pharmacokinetics of major metabolites of carbasalate calcium in broilers following oral administration JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS 2011.01
99. Development of a high-performance liquid chromatography method for the simultaneous quantification of four organoarsenic compounds in the feeds of swine and chicken Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
100. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction method for the determination of benzimidazole residues in edible tissues Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
101. Development of a liquid chromatography-tandem mass spectrometry with pressurized liquid extraction for determination of glucocorticoid residues in edible tissues ournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
102. Development of an HPLC-UV method for the simultaneous determination of tetracyclines in muscle and liver of porcine, chicken and bovine with accelerated solvent extraction Food Chemistry 2011.01
103. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2011.01
104. Development and validation of an indirect competitive enzyme-linked immunosorbent assay for monitoring quinoxaline-2-carboxylic acid in the edible tissues of animals Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment Abbreviated source title:Food Addit. Contam. Part A Chem. Anal. Control Exposure Risk Assess. 2011.01
105. Metabolic pathways of trichothecenes DRUG METABOLISM REVIEWS 2010.01
106. Comparative Metabolism of T-2 Toxin by the Fractions of Hepatocytes from Rats, Pigs, Chickens and Carps DRUG METABOLISM REVIEWS 2010.01
107. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with pressurized liquid extraction for simultaneous quantification and confirmation of cyromazine, melamine and its metabolites in foods of animal origin ANALYTICA CHIMICA ACTA 2010.01
108. The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken TOXICOLOGY LETTERS 2010.01
109. Interactions of NADPH oxidase, renin-angiotensin-aldosterone system and reactive oxygen species in mequindox-mediated aldosterone secretion in Wistar rats TOXICOLOGY LETTERS 2010.01
110. Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro ANALYTICAL AND BIOANALYTICAL CHEMISTRY 2010.01
111. Long-term dose-dependent response of Mequindox on aldosterone, corticosterone and five steroidogenic enzyme mRNAs in the adrenal of male rats TOXICOLOGY LETTERS 2010.01
112. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals ANALYTICA CHIMICA ACTA 2010.01
113. Development of an HPLC-UV method for the simultaneous determination of tetracyclines in muscle and liver of porcine, chicken and bovine with accelerated solvent extraction FOOD CHEMISTRY 2010.01
114. Simultaneous determination of amitraz and its metabolite residue in food animal tissues by gas chromatography-electron capture detector and gas chromatography-mass spectrometry with accelerated solvent extraction JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2010.01
115. Development of a high-performance liquid chromatography method to monitor the residues of benzimidazoles in bovine milk JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 2010.01
116. Metabolism of mequindox in liver microsomes of rats, chicken and pigs RAPID COMMUNICATIONS IN MASS SPECTROMETRY 2010.01
117. Residue Depletion and Tissue-Plasma Correlation of Methyl-3-quinoxaline-2-carboxylic Acid after Dietary Administration of Olaquindox in Pigs JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010.01
118. Tissue Depletion and Concentration Correlations between Edible Tissues and Biological Fluids of 3-Amino-2-oxazolidinone in Pigs Fed with a Furazolidone-Medicated Feed JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2010.01
119. ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro CHEMICO-BIOLOGICAL INTERACTIONS 2010.01
120. Quantification of Mutated Alleles of 23S rRNA in Macrolide-Resistant Campylobacter by TaqMan Real-Time Polymerase Chain Reaction FOODBORNE PATHOGENS AND DISEASE 2010.01
121. Acute and subchronic toxicological evaluation of Mequindox in Wistar rats REGULATORY TOXICOLOGY AND PHARMACOLOGY 2010.01
122. Population pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin in chicken based on retrospective data, incorporating first-pass metabolism Journal of Veterinary Pharmacoogy and Therapeutics 2010.01
123. Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of glucocorticoid residues in edible tissues of swine, cattle, sheep, and chicken FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 2010.01
124. Comparative Metabolism of T-2 Toxin by the Fractions of Hepatocytes from Rats, Pigs, Chickens and Carps DRUG METABOLISM REVIEWS 2010.01
125. Comparative Metabolism of T-2 Toxin by the Fractions of Hepatocytes from Rats, Pigs, Chickens and Carps DRUG METABOLISM REVIEWS 2010.01
126. Determination of sodium nifurstyrenate and nitrovin residues in edible food by liquid chromatography-tandem mass spectrometry after ultrasound-assisted extraction Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2010.01
127. Simultaneous determination of amitraz and its metabolite residue in food animal tissues by gas chromatography-electron capture detector and gas chromatography-mass spectrometry with accelerated solvent extraction Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2010.01
128. Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with pressurized liquid extraction for simultaneous quantification and confirmation of cyromazine, melamine and its metabolites in foods of animal origin Analytica Chimica Acta 2010.01
129. Development of a high-performance liquid chromatography method to monitor the residues of benzimidazoles in bovine milk Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2010.01
130. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals Analytica Chimica Acta 2010.01
131. Application of a modified enzyme-linked immunosorbent assay for 3-amino-2-oxazolidinone residue in aquatic animals Analytica Chimica Acta 2010.01
132. Application of electrospray ionization hybrid ion trap/time-of-flight mass spectrometry in the rapid characterization of quinocetone metabolites formed in vitro Analytical and Bioanalytical Chemistry 2010.01

科研项目

1.畜禽用新原料创制与产品开发 2017-2020
2.新型动物药剂创制与产业化 2017.01
3.美洛昔康残留检测方法验证复核。勃林格殷格翰国际贸易(上海)有限公司横向课题,2017.03
4.头孢氨苄及卡那霉素A的残留检测方法验证复核。勃林格殷格翰国际贸易(上海)有限公司横向课题,2017.03
5.猪肌肉中恩拉霉素的残留检测方法。石家庄高科动物保健品有限公司横向课题,2017.04
6.武汉市动物性食品残留检测工程技术研究中心考核奖励。武汉市科技局2016年市级科计创新平台奖励,2016.01
7.农产品质量安全风险评估。农业行业标准制定和修订(农产品质量安全监管专项)项目,2016.01
8.高风险兽药安全试验及风险评估。兽药行业标准制定和修订项目,农财发[2016]25号,2016.01
9.畜禽肝脏、肾脏等主要可食组织中12类150种混合化学污染物同步检测-液相色谱-高分辨串联质谱方法。农业部行业标准制定与修订(农业行业标准)项目,农财发[2016]29号,2016.01
10.动物性食品中喹乙醇及代谢物残留量的测定 高效液相色谱法(或液相色谱-串联质谱法)。农业部行业标准制定与修订(农业行业标准)项目,农财发[2016]29号,2016.01
11.奶和奶粉中青霉素类药物多残留的测定 液相色谱-串联质谱法。农业部行业标准制定与修订(农业行业标准)项目,农财发[2016]29号,2016.02
12.新兽药研发合作协议-乙酰吉他霉素在猪临床前试验(二期)。2015.01
13.兽药残留检测方法标准研究制定。华中农业大学自主科技创新基金项目(编号2662015PY021),2015.01
14.快速检测试纸条。漯河艾能生物技术有限公司。横向课题。2015.01
15.喹乙醇风险评估与风险因子跟踪调查。农业行业标准制定和修订(农产品质量安全监管)项目,2015.02
16.禽畜产品兽药残留预警技术。农业部948项目(编号2014S12),2014.01
17.农产品质量安全风险评估。农业行业标准制定和修订(农产品质量安全监管)项目,2014.02
18.湖北省高端人才引领培养计划第一层次人选。2014.05
19.阿莫西林克拉维酸钾注射液在猪的生物等效性试验和休药期验证试验。浙江海正药业股份有限公司横向课题,2014-2015
20.乙酰吉他霉素在猪临床前试验。 广东海纳川药业股份有限公司横向课题,2013- 2014
21.潮霉素B预混剂在肉鸡的临床试验。浙江海正药业股份有限公司横向课题,2013-2014
22.加米霉素注射液休药期试验。齐鲁动物保健品有限公横向课题,2013-2014
23.兽药残留新型检测技术国际合作与交流。农业部948项目(编号:2013-S14),2013-2014
24.杆菌肽锌预混剂在猪残留消除实验。福建绿康生化股份有限公司横向课题,2013.02
25.磺胺甲基异恶唑在鸡的有效性与安全性试验。上海恒丰强兽药公司项目,2012- 2013
26.阿维拉霉素在鸭的生产性能改善试验。礼莱动物保健品公司项目,2012-2013
27.制订喹烯酮在猪中的最大残留限量标准。农业部农业行业标准制修订项目(农财发[2012]56号),2012-2013
28.有害化合物残留早期鉴定及预警技术研究。农业行业科技专项课题(201203 040-3),2012-2016
29.兽药残留快速检测技术联合研发。国家国际科技合作计划重点项目(国科外字[2012]27号),2012-2014
30.开展高风险性兽药安全性评价及风险评估、兽药休药期试验及制定工作。农业行业标准制修订项目(农财发[2012]34号),2012-2013
31.喹噁林类兽药安全试验及风险评估。农业行业标准制修订项目(农财发[2012]36号),2012-2013
32.兽药残留检测国家重点实验室(培育)科研基地(A类)。华中农业大学培育专项(2011PY151),2011-2013
33.动物源食品中抗菌药残留微生物学高通量筛选技术改进与产业化研究。华中农业大学自主科技创新基金标志性成果培育专项(2011PY058),2011-2012
34.动物性食品中7种四环素类药物残留量测定 高效液相色谱法。农业部农业行业标准制定和修订项目(农财发[2011]53号),2011-2013
35.抗菌剂耐药性安全评价及监测技术,鲜乳激素类药物风险评估及检测方法。农业部兽药质量安全监管项目(农财发[2011]6号),2010-2012
36.兽药残留消除规律试验与风险评估。农业部兽药行业标准制定和修订项目(农财发[2011]8号),2011-2013
37.动物性食品中双甲脒气-质法、锥虫胂胺和林可霉素液-质法、红霉素、林可霉素和吉他霉素液相法。农业部农业行业标准制定和修订项目(农财发[2010]49号),2010-2012
38.喹烯酮基础毒理学研究。十一五国家科技支撑计划项目-我国自主创制兽药残留限量标准研究课题(2009BADB7B05-01),2010~2012
39.莱克多巴胺等高风险兽药残留检测、安全监测、消除规律及评估研究。农业部2010年兽药行业标准制订和修订(农财发[2010]49号),2010-2011
40.有机胂类和氟喹诺酮类风险评估。农业部兽药质量安全监管项目(农财发[2010]41号),2010-2012
41.抗菌剂耐药性安全性评价与耐药性监测研究及技术标准制定。农业部兽药质量安全监管项目(农财发[2010]41号),2010-2012
42.动物性食品中兽药残留最高限量标准。农业行业标准制修订项目(农财发[2009]105号),2009-2010
43.牛奶中大环内酯类LC-MS/MS法、双甲脒、噻苯咪唑、苄星青霉素/普鲁卡因残留检测法。2009年第二批农产品质量安全应急工作项目(农财发[2009]193号),2009-2011
44.抗菌剂耐药性安全评价和耐药性监测及技术标准制定。农业部兽药安全监管项目(农财发[2009]105号),2009-2011
45.喹噁啉类和单端孢霉烯族毒素体内代谢研究。973项目子课题,2009-1013
46.动物性食品中硝基酚钠、五氯酚钠、氮哌酮及其代谢物液相色谱-串联质谱法,酒石酸锑钾气相色谱-质谱法。2009年农业行业标准制订和修订项目(农财发[2009]105号),2009-2011
47.动物性食品中吡利霉素、聚醚类药物(4种)HPLC法,双甲脒、壮观霉素/林可霉素/克林霉素气质法,氨基苷类(11种)、青霉素类(9种)LC-MS/MS法,吡啶醋酸汞/醋酸汞原子荧光法。2009年农业行业标准制订和修订项目(农财发[2009]105号),2009-2011
48.莱克多巴胺在动物内脏组织中残留消除规律试验研究及其相关资料收集分析。2009年农业行业标准制订和修订项目(农财发[2009]105号),2009-2010
49.我国兽用处方药确定原则及清单的制定。中国兽医药品监察所,2009.02
50.畜禽产品中有害物质形成原理与控制途径研究。国家重点基础研究发展计划(973计划,2009CB118800),2009-2013
51.猪可食性组织中阿维拉霉素残留HPLC-MS/MS方法复核验证。美国礼莱公司。2008.02
52.动物性食品中糖皮质激素类残留检测方法研究。农业部2008年农产品质量安全监管专项经费(农财发[2008]91号)。2008.02
53.动物性食品中糖皮质激素类残留检测。农业部2008年农产品质量安全监管专项经费(农财发[2008]91号),2008.01
54.兽药残留安全监管项目(农财发[2008]90号),农业投入品质量监管项目,2008-2009
55.动物源性食品中呋喃苯烯酸钠、氨苯砜、喹乙醇和卡巴氧残留检测 液相色谱-串联质谱法(制定),左旋咪唑残留检测 高效液相色谱法(制定)。农业行业标准制修订项目(农财发[2008]74号),2008-2009
56.动物源性食品中糖皮质激素残留检测 液相色谱-串联质谱法(制定),喹乙醇、卡巴氧、泰乐菌素和替米考星残留标示物残留检测 酶联免疫法(制定)。农业行业标准制修订项目(农财发[2008]74号),2008-2009
57.动物源性食品中β-受体激动剂、硝呋烯腙、大环内酯类残留检测液相色谱-串联质谱法(制定),动物源食品中对乙酰氨基酚、水产品中青霉素残留检测 高效液相色谱法(制定)。农业行业标准制修订项目(农财发[2008]74号),2008-2009,
58.动物源食品中二甲氧苄啶的最高残留限量标准(制定)。动物性食品中兽药最高残留限量标准制修订项目,2008.01
59.武汉市动物性食品残留检测技术研发中心(武科计[2008]33号文,项目编号:200820337087).武汉市平台项目,2007-2009.
60.水产安全生产的综合示范。武汉市科技计划,2007.01
61.优质健康猪肉生产的关键技术集成与产业化示范-生猪及其可食性产品中有害残留关键检测技术的研究和示范。武汉市重大科技产业化专项(20072011 2026),2007-2009
62.土拉霉素口服溶液临床药理学及残留研究。山东六合动物保健品公司,2008-2009
63.国家兽药安全评价实验室建设。国家动物防疫体系建设计划,2007-2009
64.阿维拉霉素预混剂预防仔猪腹泻的疗效试验。美国礼莱公司,2007-2008
65.卡巴匹林在鸡的药代学研究。齐鲁动物保健公司,2007.02
66.畜禽产品安全检测新技术研究(2006BAD14B04)。十一五国家支撑计划《畜禽健康养殖与新型工业化生产模式研究及示范》项目子课题,2006-2008
67.动物源食品中阿苯哒唑、氨苄西林、庆大霉素、泰乐菌素、头孢噻呋、壮观霉素和林可霉素残留的测定-HPLC法,双甲脒残留测定-GC法。农业行业标准制定和修订项目(农财发[2007]40号),2007.01
68.水产安全生产综合示范(湖北示范区)。十一五国家科技支撑计划《食品安全关键技术》重大项目的课题(2006BAK02A22),2006-2008
69.喹噁啉类和阿苯哒唑残留标示物标准品制备。十一五国家科技支撑计划《食品安全关键技术》标准品制备课题(2006BAK02A30),2006-2008 70.喹乙醇残留单抗ELISA分析方法和快速检测试剂盒研制。湖北省高层次人才工程项目,2006.01
71.兽药残留安全性评价指南研究,猪可食性组织中AOZ测定-ELISA方法标准制订。农业行业标准制定和修订项目(农财发[2006]64号),2006.01
72.食品动物避免残留数据库及关键技术设备引进。教育部引进外智重点项目(2004-Z43),2006.01
73.食品安全关键技术研究开发与示范。武汉市产业化重大专项(20062001018,武科技[2006]42号),2006.01
74.头孢噻呋注射剂急性毒性和在猪的生物等效性研究。齐鲁动物药业,2006.01
75.动物源食品中3-甲基-喹恶啉-2-羧酸、青霉素类残留测定--HPLC法,喹恶啉-2-羧酸残留测定-GC法。农业行业标准制修订项目(农财发[2005]58号),2005.01
76.中国动物源食品避免残留数据库建立及数据利用。国家外国专家局聘请外国文教专家项目,2005.01
77.几种兽药残留的流式液相芯片检测方法及其关键技术研究。十五国家食品安全重大专项(2001BA804A53),2005.01
78.国家兽药残留基准实验室建设。国家发改委,2004.01
79.牛奶中抗菌药物残留快速检测微生物学法和青霉素类残留定量检测法及标准化。十五国家科技攻关重点课题(2004BA51A17-02),2004-2005
80.食品动物避免残留数据库及关键技术设备引进。农业部引进国际农业先进技术项目(2004-Z43),2004.01
81.国内外兽药法规研究。农业部专项,2004-2006
82.阿普拉霉素和甲基盐霉素在鱼的抗病、促生长和残留研究。美国礼莱公司合作基金,2004-2005
83.动物源性食品、饲料和饮水中喹恶啉类兽药的检测技术研究。上海市科技兴农重点攻关项目(沪农科攻字[2003]第9-9号),2004-2006
84.动物源食品中兽药(喹乙醇)残留的发生与消除研究。教育部科学技术研究重点项目(教技司[2003]225号,项目编号:104206),2004-2006
85.国内外农产品兽药残留标准的差异及相应贸易技术措施研究。商务部技术性贸易措施体系建设项目(商技四司函[2003]156号),2004.01
86.动物组织中青霉素类、硝基咪唑类、氨基苷类、四环素类、呋喃唑酮多残留HPLC检测方法。农业部兽药残留检测方法制定计划(农办牧[2003]76号),2003-2004
87.国内外兽药使用和动物源性产品药物残留数据库。商业部技术性贸易措施体系建设项目(商技三司函[2003]69号),2003-2004
88.喹乙醇代谢与残留的关系研究。教育部“跨世纪优秀人才培养计划”基金(教技函[2002]48号),2003-2005
89.兽药投入与食品安全。十五国家食品安全重大科技专项,2003.01
90.兽药残留监测方法复核。农业部残留专项基金,2003.01
91.农业部兽药残留检测基准实验室建设。国家动物保护工程项目,2003.02
92.主要违禁兽药残留快速检测方法和试剂盒研究。“十五”国家食品安全重大科技专项(2001BA804A18-01),2002-2005
93.食品中持久性有机污染物的膳食暴露/人体复合与健康效应的研究。863计划国际合作(2002AA217 031),2002-2005
94.环丙沙星在猪和鸡的代谢与残留消除研究。国家自然科学基金(30271002),2003-2005
95.三类抗菌药物残留微生物检测方法研究。十五国家重点科技攻关(2002B A514-14),2001-2004
96.高效抗菌增效剂溴莫普淋的生产和应用技术研究。十五国家重点科技攻关(2002BA514-17-08),2001-2004
97.喹烯酮的代谢和残留研究。企业基金,2002.01
98.喹赛多应用技术研究。湖北省“111”人才择优项目(鄂人函[2001]164号),2001.01
99.环丙沙星比较代谢研究。美国NIH国际合作项目,2001.01
100.抗菌药物残留活体快速检测方法,3-甲基-喹恶啉-2-羧酸、地塞米松的合成与残留检测方法建立。农业部残留重点专项(农办牧[2002]4号),2001-2002
101.抗菌药物残留快速检测方法标准制订。农业部行业标准制修定(农市发[2001]19号,03148),2001-2002
102.制订克伦特罗在牛肝、肌肉组织,卡巴氧在猪肉、肝、肾,镇静药类(包括氯丙嗪、异丙嗪等在猪肾,阿苯唑在猪、牛、羊组织中中残检测方法。农业部兽药残留专项(农牧药发[2000]72号),2000-2001
103.喹赛多对猪营养物质吸收利用和激素分泌的影响研究。教育部骨干教师培养计划,2000-2001
104.克伦特罗和氯霉素的残留监控检测。农业部残留监控计划(农牧药发[2000]37号),2000.01
105.动物屠宰前兽药残留控制的系列检测方法。国家948项目(992112),1999-2001
106.动物源食品中残留物质监控。农业部残留专项(农(财预[1999]8号),1999.01
107.恩诺沙星残留检测方法。农业部防疫专项(农(财事) [1999]27号),1999.01
108.兽医药理学及毒理学进展的讲学与培训。国家自然科学基金(199110421608),1999.01
109.喹赛多促进猪生长的内分泌药理学研究。国家自然科学基金(39870596),1999-2001
110.新霉素和庆大霉素残留量检测方法复核。农业部重点专项基金(农牧药发(1999)2号),1999.02
111.非营养性饲料添加剂喹赛多的应用技术研究。湖北省重点攻关(982P0801),1998-2000
112.环丙沙星在链球菌病猪的多剂量动力学研究。国家自然科学基金(3957055),1996-1998。
113.喹肼氰研究开发和应用技术研究。国家科技攻关项目(96-009-02-04-05),1996-1998
114.药物残留快速检测方法研究。国家科技攻关项目(96-005-02-04-04),1996-2000
115.20余种兽药的残留检测方法、残留律规和法规标准制订。农业部重点专项基金,1998.01
116.运动、能量限制和应激对免疫功能的影响。美国农业部国际合作项目,1997 .01
117.抗菌药物残留的快速检测方法研究。农业部重点专项,1997.01
118.动物专用新药喹塞多的研制与开发。农业部重点攻关(95牧-02-04-12),1996-1998
119.酒石酸泰乐菌素在肉鸡的残留研究。农业部重点专项,1995-1997,
120.磷酸泰乐菌素在肉鸡的残留研究。农业部重点专项,1995-1997
121.氨苄青霉素在鸡的残留检测方法研究。农业部重点专项,1996-1998
122.氨苄青霉素在猪的残留研究。农业部重点专项,1996-1998
123.饲料添加剂的毒理学及公共卫生学研究。农业部重点专项,1995-1996
124.马杜霉素胺饮水剂的临床毒理学评价。企业基金,1997.01
125.猪链球菌病对抗菌药物动力学的影响机理研究。国家自然科学基金(0388022),1989-1991
126.家畜抗寄生虫药物控释制剂的研究。农业部重点攻关,1991-1995
127.家畜抗寄生虫药物的代谢动力学研究。农业部重点攻关,1986-1990
家畜抗菌药物代谢动力学研究。农业部重点攻关,1981-1985

主要奖励

1. 动物源食品中主要兽药残留物高效检测关键技术。国家技术发明奖,二等奖,2016.121,第,1完成人
2. 喹噁啉类三种兽药的食品安全性评价与风险管控技术研究。湖北省人民政府,科技进步奖,一等奖,2016.12,第,1完成人
3.动物源食品有害残留高效检测核心试剂创制与产品研发。湖北省人民政府,技术发明奖,一等奖,2015.12。证书编号:2015F- 042-1-011-004-R01,第,1完成人
3. 兽用抗菌药和违禁药残留高效检测标准制定与产品创制。北京大北农集团,第九届大北农科技奖成果奖,一等奖,2015.11。证书编号:2015-DBNSTA-01-0098,第,1完成人
4.兽药残留检测方法标准研究制订。湖北省人民政府,科学技术进步奖,一等奖,2013。证书编号:2013J-226-1-034-029-R01,第,1完成人
5.湖北省归国华侨联合会、何亮胜侨界科技奖励基金理事会,科技奖励,三等奖,2011。证书编号:2011929
6.动物源性食品中糖皮质类药物残留检测液相色谱-串联质谱法。湖北省技术监督局,标准创新贡献奖,一等奖,2010。证书编号:2010-1-02-02,第,1完成人
7.兽药残留检测关键技术创新与配套集成研发。教育部,教育部高等学校科学研究优秀成果奖科学技术进步奖,一等奖,2008。证书编号:2008-171,第,1完成人
8.动物可食性组织中兽药残留系列分析方法研究。湖北省人民政府,科学技术进步奖,二等奖,2008。证书编号:2008J-251-2-063-010-R01,第,1完成人
9.动物专用新药喹噻多的研究开发。北京大北农集团,大北农科技奖科技促进奖,二等奖,1999。证书编号:98-414,第,1完成人
10.传染病对兽用抗菌药物动力学的影响研究。教育部,科技进步奖,三等奖,1998。
11.家畜抗菌药物代谢动力学研究。国家教委科技进步奖(甲类),三等奖,1993
12.磺胺二甲嘧啶在急性巴氏杆菌病兔的药动学研究。中国畜牧兽医学会青年科技奖一等,1989

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