• 余梅

• 系所

  动物遗传育种系

• 职称

  三级教授

• 办公房间

  第一综合楼B座

• email

  yumei@mail.hzau.edu.cn

• 讲授课程

  《生物统计附试验设计》、《兽医统计及试验设计》、《试验设计与数据分析》等

个人简介

余梅，华中农业大学教授、博士生导师。教育部新世纪优秀人才支持计划（2008）和湖北省杰出青年基金获得者（2008）。中国畜牧兽医学会动物遗传育种分会理事。主持承担国家自然科学基金重点项目，国家自然科学基金，“863”项目，国家转基因专项重大项目子任务及重点项目，“973” 项目子任务及科技支撑计划子课题等10余项。在《Biology of Reproduction》, 《Reproduction》,《Mammalian Genome》,《Animal Genetics》等SCI收录刊物上发表文章40余篇，获得七项由国家知识产权局授权的发明专利。

教育经历

1985.9至1989.6 华中师范大学，生物学，学士
1992.9至1995.6 华中农业大学，动物遗传育种学， 硕士
1999.9至2003.1 华中农业大学，动物遗传育种学， 博士
2004.4月至2006.9月，美国依阿华州立大学博士后研究。

工作经历

1989. 12至1992.8, 武汉市农业科学院培训处, 助教
1995. 7至2001.12, 华中农业大学畜牧兽医学院，讲师
2002. 1至2006.12，华中农业大学动物科技学院，副教授
2006. 12至今，华中农业大学动物科技学院，教授

研究领域

家畜重要经济性状相关基因的鉴定，主要研究方向是结合基因组学、功能基因组学和统计生物信息学等方法研究猪母胎互作的分子机制，鉴定与生长、繁殖性状相关的调控基因。

科研成果

国家自然科学基金重点项目：猪胚胎附植定位类型差异机制解析及关键基因挖掘，项目负责人， 2018-2022
国家自然科学基金面上项目：转录因子ZEB2介导的调控猪胎盘褶皱绒毛膜上皮细胞形状转换的机制研究，项目负责人， 2016-2019
国家重点基础研究发展规划项目：猪繁殖力的生理学及相关遗传调控机理， 课题骨干，2014-2018
国家高技术研究发展计划：羊重要经济性状功能基因组学研究，任务负责人，2013-2017
国家自然科学基金面上项目：不同品种猪妊娠早期子宫液差异分泌蛋白鉴定及其对附植的调控机制研究，项目负责人，2013-2016

科研项目

Linjun Hong, Kun Han, Kejia Wu, Ruize Liu, Ji Huang, Joan K Lunney, Shuhong Zhao and Mei Yu. E-cadherin and ZEB2 modulate trophoblast cells differentiation during placental development in pigs.Reproduction, 2017, 154：765-775. DOI: 10.1530/REP-17-0254.
Teng, Linjun Hong, Ruize Liu, Ran Chen, Xinyun Li , Mei Yu. Cellular localization and regulation of expression of the PLET1 gene in porcine placenta. Int. J. Mol. Sci. 2016, 17, 2048; doi:10.3390/ijms17122048.
Zhichao Zhao, Guangbin Liu, Xinyun Li, Ji Huang, Yujing Xiao, Xiaoyong Du, Mei Yu. Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression. PLoS One. 2016 ,11(4):e0153936. doi: 10.1371/journal.pone.0153936.
Wanbao YANG, Qinqun LI, Bo SU, Mei YU，MicroRNA-148b promotes proliferation of hair follicle cells by targeting NFAT5. Front. Agr. Sci. Eng. 2016, 3(1): 72–80. DOI: 10.15302/J-FASE-2016089.
Linjun Hong, Xiangdong Xu, Ji Huang, Minggang Lei, Dequan Xu, Shuhong Zhao, Mei Yu. Difference in expression patterns of placental cholesterol transporters, ABCA1 and SR-BI, in Meishan and Yorkshire pigs with different placental efficiency. Scientific Reports, 2016, 6:20503, DOI: 10.1038/srep20503.
Jiangnan Huang, Ruize Liu, Lijie Su, Qian Xiao Mei Yu. Transcriptome Analysis Revealed the Embryo-Induced Gene Expression Patterns in the Endometrium from Meishan and Yorkshire Pigs. Int. J. Mol. Sci. 2015, 16, 22692-22710.
Ruize Liu, Min Wang, Lijie Su, Xiaoping Li, Shuhong Zhao, Mei Yu. The expression pattern of microRNAs and the associated pathways involved in the development of porcine placental folds that contribute to the expansion of the exchange surface area. Biology of Reproduction. 2015, 93(3):62, 1–13.
Guangbin Liu, Ruize Liu, Xiaohui Tang, Jianhua Cao, Shuhong Zhao and Mei Yu. Expression Profiling Reveals Genes Involved in the Regulation of Wool Follicle Bulb Regression and Regeneration in Sheep. Int. J. Mol. Sci. 2015, 16, 9152-9166.
Linjun Hong, Chunyan Hou, Xiaoping Li, Changchun Li, Shuhong Zhao, and Mei Yu，Expression of heparanase is associated with breed-specific morphological characters of placental folded bilayer between Yorkshire and Meishan pigs. Biology of Reproduction, 2014，90(3) :56,1-9.
Lijie Su, Ruize Liu, Wei Cheng, Mengjin Zhu, Xiaoping Li, Shuhong Zhao, Mei Yu ,Expression patterns of microRNAs in porcine endometrium and their potential roles in embryo implantation and placentation. PLoS ONE, 9(2): 2014, e87867. doi:10.1371 /journal.pone.0087867.
Linjun Hong, Chunyan Hou, Xiaoping Li, Changchun Li, Mei Yu, Expression pattern of CD34 at the maternal-fetal interface during pregnancy in pigs. Reproduction in Domestic Animals, 2013, doi: 10.1111/rda.12157.
Xiaoping Li, Zongping Zhang, Jiangnan Huang, Lijie Su, Mengjin Zhu, Mei Yu. Expression Pattern of Genes Involved in Maternal Immune Regulation during the Peri-implantation and Midgestation in Meishan Pigs. Genes & genomics, 2013, DOI 10.1007/s13258-013-0087-3.
Lijie Su, Shuhong Zhao,Menjing Zhu, Mei Yu, Differential expression of microRNAs between porcine placentas on days 30 and 90 of gestation. Reproduction, Fertility and Development. 2010, 22, 1175-1182.
Liu K, Wang G, Zhao SH, Liu B, Huang JN, Bai X, Yu M, Molecular characterization, chromosomal location, alternative splicing and polymorphism of porcine GFAT1 gene. Molecular Biology Reports. 2010, 37(6):2711-7.
Huang J, Zhao S, Zhu M, Wu Z, Yu M. Sequence and expression analyses of porcine ISG15 and ISG43 genes. Comp Biochem Physiol B Biochem Mol Biol. 2009, 153 (4):301-9.
Xue Bai, Shuhong Zhao, Xiangdong liu, Mengjin Zhu, Zhenfang Wu, Mei Yu, The porcine RNASE1, ANG and RNASE6 genes: molecular cloning, polymorphism detection and the association with haematological parameters. Molecular Biology Reports.2009, 36:2405-2411.
Yu M, Geiger B, Deeb N, Rothschild M F., Investigation of TXNIP (thioredoxin-interacting protein) and TRX (thioredoxin) genes for growth-related traits in pigs. Mammalian Genome，2007, 18:197-209.
Liu K, Zhao SH, Liu B, Fan B, Li CC, and Yu M, Assignment of solute carrier family 2 (facilitated glucose transporter), members SLC2A2, SLC2A3, SLC2A5, SLC2A8 and SLC2A12 to porcine chromosomes by somatic cell and radiation hybrid panel mapping. Archive of Animal Breeding. 2007, 50：114-115.
Yu M, Geiger B, Deeb N & Rothschild MF, Liver X receptor alpha and beta genes have the potential role on loin lean and fat content in pigs. J Anim Breed Genet 2006; 123(2):81-88.
Yu M, Y F Wang, M. F.W. te Pas, M. Yerle, B Liu, B Fan, T Xiong, K Li, Investigation of the porcine PA28 activator -subunit (PSME3) gene: isolation, polymorphism and its chromosomal localization. J Anim Breed Genet. 2004, 121:142–8.
Yang J, Li K Liu, Yerle B, Fan B,Xiong T,Yu M, Assignments of GRB7, GCN5L2, COL1A1 and TBCD to pig chromosome 12 by radiation hybrid mapping. Cytogenet Genome Res.2003, 103:204L, DOI: 10.1159/000076312.
Yu M, Liu B, Yerle M, Zhu M, P. Pan, B. Fan and K. Li, Physical mapping of the rod cGMP-phosphodiesterase -subunit (PDE6G) gene to pig chromosome 12. Anim. Genet. 2003, 34(1): 76-77.

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